Fever,rash,childhood infections

2016 Article - "Cluster of human parechovirus infections as the predominant cause of sepsis in neonates and infants, Leicester, United Kingdom, 8 May to 2 August 2016" (pdf, 129KB)

Summary: In this study they report an unusually high number of cases (n = 26) of parechovirus infections in the cerebrospinal fluid (CSF) of neonates and infants admitted with sepsis in the United Kingdom during 8 May to 2 August 2016. Although such infections in neonates and infants are well-documented, parechovirus has not been routinely included in many in-house and commercial PCR assays for CSF testing. Clinicians should consider routine parechovirus testing in young children presenting with sepsis. In this publication the FTD EPA kit was internally validated for CSF testing!

Kits used: FTD EPA

2016 Article - "Predominance of enterovirus B and echovirus 30 as cause of viral meningitis in a UK population" (limited access)

Summary: Enteroviruses are the most common cause of aseptic or lymphocytic meningitis, particularly in children. With reports of unusually severe neurological disease in some patients infected with enterovirus D68 in North America, and a recent increase in the number of paediatric enterovirus meningitis cases presenting in this UK Midlands population, a retrospective regional surveillance study was performed.

Kit used: FTD EPA
Website link

2015 Poster - "Fever and rash panel of FTD real-time multiplex RT-PCR is a useful diagnostic tool in children presenting with fever and rash" (pdf, 215KB)

Summary: To evaluate the use and efficacy of the fever and rash panel of the Fast-Track Diagnostics (FTD) multiplex reverse transcriptase polymerase chain reaction (RT-PCR) as a diagnostic tool in children presenting with fever and maculopapular rash illness. This was used in addition to standard practices of bacterial culture of throat swabs and blood.

Kit used: FTD Fever and rash

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