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Fast Track Diagnostics expands its lyophilised portfolio
New educational presentation - Lyophilised tests
Importance of human Parechovirus testing
New recombinant norovirus GII.P16-GII.2
2017 Article - "The potential influence of human parainfluenza viruses detected during hospitalization among critically ill patients in Kuwait, 2013–2015" (pdf, 485KB)
Summary: The aim of this study is to describe the spectrum, incidence and clinical features of of human parainfluenza viruses (PIV)-associated infections diagnosed during the hospital stay of patients admitted to pediatric intensive care unit (PICU) and intensive care unit (ICU) of 5 medical centers across Kuwait.This was a population-based, retrospective study from 2013 to 2015. Specimens were analyzed by FTD Respiratory pathogens 21. This analysis was performed using the database of Virology Unit, Mubarak Al-Kabeer Hospital. Data from 1510 admitted patients with suspected respiratory viral infections was extracted.The database contained a total of 39 (2.6%) patients infected with PIV (53.8% male and 46.2% females) and 20 (51.3%) were under 1 year of age. The most frequently isolated type was type 3 (28, 71.8%) followed by type 1 (9, 23.1%). At admission the most common clinical diagnosis was pneumonia in 12 patients (30.8%, p < 0.05) followed by bronchiolitis in 10 patients (25.6%).PIV plays an important yet unrecognized role in the outcomes of PIUC and ICU patients. These results contribute to the limited epidemiologic data of PIV in PIUC and ICU in this region.
Kit used: FTD Respiratory pathogens 21
2017 Article - "Viral aetiology of bronchiolitis in hospitalised children in Qatar" (pdf, 836KB)
Summary: Bronchiolitis is considered one of the earliest and most common causes of hospitalisation in young children. Development of molecular technologies allowed a better understanding of bronchiolitis aetiology. Results from cohort studies evaluating the association between single, multiple viral infections and clinical outcomes are conflicting. Data on viral bronchiolitis in children were found to be limited in Qatar. This study aimed to determine frequency and seasonal trends of viral pathogens causing acute bronchiolitis, and to explore association between viral pathogens, disease severity and length of stay (LOS). Multiplex, real-time, polymerase chain reaction (RT-PCR) using FTDResp21 kit (Fast Track Diagnostics, Silema, Malta) was used for the detection of respiratory pathogens.
Kit used: FTD Respiratory pathogens 21
2017 Article - "Genotyping of human rhinovirus in adult patients with acute respiratory infections identified predominant infections of genotype A21" (pdf, 1MB)
Summary: The aim of this study was the assessment of the prevalence of HRV and its specific genotypes in patients suffering from acute respiratory tract infections (ARTIs).
Samples from 147 adult inpatients with community-acquired pneumonia (CAP) and 291 adult outpatients with upper ARTIs (URTIs) were collected. The presence of HRVs and other common respiratory pathogens were screened using the FTD Respiratory pathogens 21 plus kit. HRV was detected in 42 patients, with 35 species A, five B and two C. Seventeen genotypes were identified, and HRV-A21 ranked the highest (9/42, 21.4%). The HRV-A21 genome sequenced in this study contained 12 novel coding polymorphisms in viral proteins. The infections of HRV-A21 virus obtained in this study could not be neutralized by antiserum of HRVA21 prototype strain (VR-1131), indicating remarkable antigenic variation.
The results highlight an unexpected infection of genotype HRV-A21 in the clinic, indicating the necessity of precise genotyping and surveillance of HRVs to improve the clinical management of ARTIs.
Kit used: FTD Respiratory pathogens 21 plus
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New educational presentation - FTD Respiratory infections kits